猪异位部分肝移植的血液动力学变化

目的：探讨猪异位部分肝移植术中血流动力学的变化。方法：10头幼猪随机分成供体组（5只）和受体组（5只），受体猪参照Terpstra的方法进行异位部分肝移植，受体猪右颈外动脉置管监测术中动脉压，经右颈外静脉放置5F Swan-Ganz导管监测术中血流动力学参数，结果：异位部位移植术中心输出量及每搏量，外周血管阻力均有显著改变（P＜0．01或P＜0．05），虽有血压下降，心率增快，但无显著意义（P＞0．05），肺动脉楔嵌压，平均肺动脉压无显著变化（P＞0．05），结论：异位肝移植术中血液动力学可发生剧烈波动，血液动力学的监测调节十分重要。

Changes of hemodynamics during heterotopic partial liver transplantation in pigs

Objective To study the changes of hemodynamics during heterotopic partial liver transplantation (HPLT) in pigs. Methods 10 young pigs after intravenous anesthesia were divided into two groups: donor group (5 pigs) and recipient group (5 pigs). In recipient pigs, a catheter inserted to right cervical artery was used to monitor artery bood pressue, and Swasn-Ganz catheter inserted via right cervical vein was used to monitor hemodynamics during operation.Results There were significant changes in CO, SV and SVR (P<0.01 or P<0.05); although decreasing in MAP and increasing in HR occurred during operation, but no significance(P>0.05) was found. There were no significant changes in PCWP and PAP during HPLT (P>0.05). Conclusions There is significant hemodynamic fluctuation during HPLT. It is very important that to monitor hemodynamics, prevent and manage hemodynamics disturbance durig HPLT