氟哌噻吨-美利曲辛联合西沙比利治疗功能性消化不良32例

目的：探讨抗抑郁药氟哌噻吨-美利曲辛（黛力新）联合西沙比利治疗功能性消化不良（functional dyspepsia，FD）的临床疗效。方法：对门诊64例FD的患者随机分成治疗组和对照组，均予以西沙比利5mg。每日3次，餐前15-30分钟口服。治疗组加用氟哌噻吨-美利曲辛每日早晨及中午各1片口服。结果：治疗4周后统计结果：治疗组显效42％，有效43％，总有效率85％，疗效与对照组比较差异有极显著性，P〈0．01。结论：氟哌噻吨-美利曲辛与西沙比利治疗功能性消化不良疗效较好。

Effective observation on FD treated by flupentixol/melitracen combined with cisapride

Objective:To explore the clinical effect on functional dyspepsia (FD) treated by antidepressant of flupentixol/melitracen combined with cisapride.Methods:64 patients with FD in clinic were divided into treatment group and control group at random and both were given cisapride 5mg 3times/d,orally before 15 to 30 min of dinner, meanwhile flupentixol/melitracen each a table in morning and noon were added respectively in treatment group.Results:The result showed after 4 weeks:apparent rate was 42% effective rate was 43% and the total effective rate was 85% in treatment group.The effect in the treatment had obvious defference from the control group (P<0.01).Conclusion:The effect was good in the treatment of FD by Flupentixol/melitracen combined with cisapride.