208例甲状腺乳头状癌患者颈部淋巴结转移相关因素分析

目的 探寻甲状腺乳头状癌(papillary thyroid carcinoma,PTC)患者颈部淋巴结转移的相关因素,为临床治疗决策的拟定及预后评估提供依据.方法 收集2019年6-12月在中国科学技术大学附属第一医院(安徽省立医院)头颈乳腺外科收治的208例接受手术治疗且病理证实为PTC首发病例的超声、病理及临床资...

Analysis of factors related to cervical lymph node metastasis in 208 patients with papillary thyroid carcinoma

Objective To explore the related factors of cervical lymph node metastasis in patients with papillary thyroid carcinoma(PTC),so as to provide the basis for clinical treatment decision-making and prognosis evaluation.Methods The ultrasonic,pathological and clinical data of 208 cases with PTC confirmed by pathology in the First Affiliated Hospital of the University of Science and Technology of China(Anhui Provincial Hospital)from June 2019 to December 2019 were collected.Univariate and multivariate logistic regression analysis was used to analyse the related factors of the cervical lymph node metastasis group and non-metastasis group.Results Amongst the 208 patients,126 had cervical lymph node metastasis,and the rate of metastasis was 60.6%.A significant difference was observed in the cervical lymph node metastasis rate amongst different gender,age,tumour location,tumour length and diameter,abnormal lymph nodes,tumour aspect ratio>1,multifocal lesions,bilateral lesions,capsule invasion,nodal calcification and PTC patients with nodular goitre(all P<0.05).The results of multivariate logistic analysis showed that female(OR=0.386)was a protective factor for cervical lymph node metastasis in patients with PTC,and tumour located in the lower pole(OR=3.057),abnormal lymph nodes in ultrasound(OR=6.277)and multifocal lesions(OR=2.889)were independent risk factors for cervical lymph node metastasis in patients with PTC.Conclusion Cervical lymph node metastasis in PTC patients is closely related to many factors.Paying attention to and analysing these factors have important clinical significance for clinical staging,treatment decision-making and prognosis evaluation.