2000-2003年广东省流感监测结果分析

目的]了解广东省流感流行情况,为预防和控制提供科学依据.方法]在8个流感监测点采集疑似流感病人的咽拭子,一般人群及职业人群采集血清,用9～11 d鸡胚和(或)MDCK细胞分离病毒,用常量红细胞凝集抑制法(HI)鉴定病毒;用微量半加敏红细胞凝集抑制法(micro-HI)检测流感抗体.结果]2000、2001年流感疫情较平静,2002、2003年由A(H3N2)引起的局部暴发增多,未发生大流行.4年共分离流感病毒1 425株,A(H3N2)占61. 2%、B型占27.0%、A(H1N1)占11.8%;从鸡标本分离A(H9N2)型禽流感病毒17株.一般人群血清A(H3N2)抗体阳性率较高,B(Yamagata)型较低;职业人群部分A(H9N2)禽流感抗体阳性.结论]除2003年未分离到A(H1N1)外,2000-2002年都能同时分离到A(H1N1),A(H3N2)亚型和B型.做好流感监测对控制流行与预测有重要意义.

Analysis on Influenza Surveillance in Guangdong, China (2000-2003)

-Objective- To investigate the epidemiological status of influenza viruses in Guangdong for the disease control. -Method-] Throat swab, gargling specimens and sera were collected from influenza-like cases. Influenza viruses were isolated by MDCK cells or embryonated eggs aged 9~11 days and identified by hemagglutination inhibition(HI)test. Serum antibody was detected with micro-HI test. -Results- The influenza activity was mild to moderate 2000-2001. The local outbreaks of influenza A (H3N2) were increased in 2002-2003, but no severe influenza epidemics occurred. 1 425 viruses were isolated from 2000 to 2003. 61.2% were Type A (H3N2), 11.8% were Type A (H1N1), 27.0% were Type B. 17 strains for Type A (H9N2) viruses were isolated from chickens. In general population, The antibody positive rate for Type A (H3N2) was at higher level and at lower level for B(Yamagata). In occupational population, antibody for Type A(H9N2) was partly positive. -Conclusion- Type A (H1N1),A (H3N2) and B of influenza viruses can be isolated from 2000 to 2002 except 2003 in Guangdong. Influenza surveillance will play an important role in influenza control and epidemic predicting.