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Effect of dose adjustments on the efficacy and safety of tofacitinib in patients with rheumatoid arthritis: a post hoc analysis of an open-label,long-term extension study (ORAL Sequel)
Authors:Mueller  Ruediger B  Schulze-Koops  Hendrik  Furst  Daniel E  Cohen  Stanley B   Kwok  Kenneth  Wang  Lisy  Killeen  Tim  von Kempis  Johannes
Institution:1.Rheumazentrum Ostschweiz, St. Jakobsstr. 20, 9000, St. Gallen, Switzerland
;2.Division of Rheumatology and Immunology, Kantonsspital St. Gallen, St. Gallen, Switzerland
;3.Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, Ludwig-Maximilians-University Munich, Munich, Germany
;4.UCLA, Los Angeles, CA, USA
;5.University of Washington, Seattle, WA, USA
;6.University of Florence, Florence, Italy
;7.Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, USA
;8.Pfizer Inc, New York, NY, USA
;9.Pfizer Inc, Groton, CT, USA
;10.Pfizer AG, Zürich, Switzerland
;
Abstract:Clinical Rheumatology - We assess the impact of switching versus staying on the same tofacitinib dose on efficacy and safety in patients with rheumatoid arthritis (RA). ORAL Sequel was an...
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