| 夏至草生物碱对失血性休克大鼠淋巴微循环的影响 |
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| 引用本文： | 张玉平,刘艳凯,姜华,赵自刚,杜舒婷,牛春雨.夏至草生物碱对失血性休克大鼠淋巴微循环的影响[J].中国微循环,2006,10(3):166-167. |
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| 作者姓名： | 张玉平 刘艳凯 姜华 赵自刚 杜舒婷 牛春雨 |
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| 作者单位： | 075029,河北张家口,河北北方学院基础医学部病理生理教研室 |
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| 基金项目： | 河北省中医药管理局科研项目 |
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| 摘 要： | 目的 探讨夏至草生物碱（AHL）对失血性休克大鼠淋巴微循环的影响。方法Wistar大鼠16只。随机分成夏至草生物碱组（AHL组）和生理盐水组（NS组，n=8），经颈总动脉放血复制大鼠失血性休克模型．观察AHL对肠系膜淋巴微循环的影响。结果 失血性休克时，肠系膜淋巴微循环出现明显障碍。AHL可明显使肠系膜淋巴管口径扩张，收缩幅度增大，收缩频率加快，收缩性指数升高，其作用显著优于NS组（P〈0．05）。结论 AHL能明显改善失血性休克大鼠的淋巴微循环障碍。
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| 关 键 词： | 夏至草 失血性休克 肠系膜 淋巴微循环 淋巴管 |
| 文章编号： | 1007-8568（2006）03-0166-02 |
| 收稿时间： | 2005-09-26 |
| 修稿时间： | 2006-01-05 |
Effects of Alkaloids from Herba Lagopsis on Lymph Microcirculation in Rats with Hemorrhagic Shock |
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| ZHANG Yu-ping, LIU Yan-kai, JIANG Hua,et al..Effects of Alkaloids from Herba Lagopsis on Lymph Microcirculation in Rats with Hemorrhagic Shock[J].Journal of Chinese Microcirculation,2006,10(3):166-167. |
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| Authors: | ZHANG Yu-ping LIU Yan-kai JIANG Hua |
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| Institution: | ZHANG Yu-ping, LIU Yan-kai, JIANG Hua, et al. |
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| Abstract: | Objective To explore the effect of alkaloids from Herba Lagopsis(AHL)on lymph microcirculation in rats with hemorrhagic shock. Methods Sixteen Wistar rats were divided into AHL and NS groups(n=8). A model of hemorrhagic shock was made in rats by blood loss from carotid, and then the effect of AHL on lymph microcirculation was observed. Results There was an obvious disturbance of the lymph microcirculation in rats with hemorrhagic shock. AHL could dilate mesenteric lymphatic(ML), increase the range of constriction, quicken the frequency of constriction and increase constrictive indexes, the effect exceeded to NS group(P<0.05). Conclusion AHL can obviously improve lymph microcirculation disturbance in rats with hemorrhagic shock. |
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| Keywords: | Herba Lagopsis Hemorrhagic shock Mesentery Lymph microcirculation Lymphatic |
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