| 热休克蛋白27与缺血-再灌注损伤关系的研究进展 |
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| 引用本文： | 叶孙益,郑树森,吴健. 热休克蛋白27与缺血-再灌注损伤关系的研究进展[J]. 国际外科学杂志, 2010, 37(5). DOI: 10.3760/cma.j.issn.1673-4203.2010.05.011 |
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| 作者姓名： | 叶孙益 郑树森 吴健 |
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| 作者单位： | 卫生部多器官联合移植重点实验室,浙江省器官移植重点实验室,浙江大学附属第一医院肝胆胰外科中心,杭州,310003;卫生部多器官联合移植重点实验室,浙江省器官移植重点实验室,浙江大学附属第一医院肝胆胰外科中心,杭州,310003;卫生部多器官联合移植重点实验室,浙江省器官移植重点实验室,浙江大学附属第一医院肝胆胰外科中心,杭州,310003 |
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| 摘 要： | 热休克蛋白27是细胞在应激状态下产生的一种小分子蛋白,具有高度保守性,在抗缺血-再损伤中发挥重要作用.随着器官移植技术的不断提高,心脏、肝脏、肾脏等器官移植越来越多,器官的缺血-再灌注损伤成为移植物存活与否的一个不可忽视的环节,研究内源性的器官保护机制,显得尤为重要.本文就热休克蛋白27与缺血-再灌注损伤的关系作一综述.
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| 关 键 词： | 热休克蛋白27 缺血-再灌注损伤 肝脏 肾脏 心脏 视网膜 |
Progress in the relationship between heat shock protein 27 and ischemia-reperfusion injury |
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| YE Sun-yi,ZHENG Shu-sen,WU Jian. Progress in the relationship between heat shock protein 27 and ischemia-reperfusion injury[J]. International Journal of Surgery, 2010, 37(5). DOI: 10.3760/cma.j.issn.1673-4203.2010.05.011 |
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| Authors: | YE Sun-yi ZHENG Shu-sen WU Jian |
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| Abstract: | Heat shock protein 27 is a small kind of protein which is produced under stress. HSP 27 is highly conservative, and plays an important role in ischemia-reperfusion injury. With the development of organ transplantation technique,the transplantation of heart,liver,kidney becomes more and more popular, the ischemia-reperfusion injury is a significant part of the management of these procedures. The endogenic research against the injury becomes more vital. This article is the first review of the relationship between heat shock protein 27 and ischemiareperfusion injury. |
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| Keywords: | Heat shock protein 27 Ischemia-reperfusion injury Liver Kidney heart Retina |
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