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经皮经肝穿刺胆道造影术下胆道活检诊断恶性阻塞性黄疸
引用本文:韩新巍,李永东,高雪梅,李天晓,管生,马南,王艳丽. 经皮经肝穿刺胆道造影术下胆道活检诊断恶性阻塞性黄疸[J]. 郑州大学学报(医学版), 2002, 37(6): 817-820
作者姓名:韩新巍  李永东  高雪梅  李天晓  管生  马南  王艳丽
作者单位:华中科技大学生物医学工程研究所,武汉,430074;郑州大学第一附属医院放射科,郑州,450052
摘    要:目的:探索经皮经肝穿刺胆道造影(PTC)下胆道活检的可行性和敏感性,明确病变的组织病理学特性,指导临床治疗。方法:24例恶性阻塞性黄疸患者,在行PTCD(经皮经肝穿刺胆道内外引流术)减黄术中,进行PTC术胆道活检。通过经皮经肝胆道穿刺通道向胆道内送入8F鞘,活检钳经鞘内送入并对病变狭窄段行胆道钳夹活检,获取多个标本,行组织病理学检查。结果:24例患者22例获得组织病理学诊断,阳性率为91.67%。病理报告胆管腺癌15例,胆管鳞癌1例,胰腺癌2例,肝癌2例,胃腺癌胆总管转移1你,硬化性胆管炎1例,阴性结果2例。结论:PTC下胆道活检是一种简单易行、准确可靠获取组织学病理依据的检查途径。

关 键 词:胆道肿瘤  经皮经肝穿刺胆道造影术  阻塞性黄疸  胆道活检  组织病理学
修稿时间:2002-06-12

Percutaneous transhepatic transluminal cholangiobiopsy in diagnosis of malignant obstructive jaundice
HAN Xinwei ),LI Yongdong ),GAO Xuemei ),LI Tianxiao ),GUAN Sheng ),MA Nan ),WANG Yanli ) )Institute of Biomedical Engineering,Huazhong University of Science and Technology,Wuhan ). Percutaneous transhepatic transluminal cholangiobiopsy in diagnosis of malignant obstructive jaundice[J]. Journal of Zhengzhou University(Medical Sciences), 2002, 37(6): 817-820
Authors:HAN Xinwei )  LI Yongdong )  GAO Xuemei )  LI Tianxiao )  GUAN Sheng )  MA Nan )  WANG Yanli ) )Institute of Biomedical Engineering  Huazhong University of Science  Technology  Wuhan )
Affiliation:HAN Xinwei 1),LI Yongdong 2),GAO Xuemei 2),LI Tianxiao 2),GUAN Sheng 2),MA Nan 2),WANG Yanli 2) 1)Institute of Biomedical Engineering,Huazhong University of Science and Technology,Wuhan 430074 2)Department of Radiology,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052
Abstract:Aim: To explore the technical feasibility and sensitivity of percutaneous transhepatic cholangiobiopsy in malignant obstructive jaundice, and guide the clinic to treat disease. Methods:A total of 24 patients with malignant obstructive jaundice who were treated by percutaneous transhepatic cholangiograph and drainage accepted percutaneous transhepatic cholangiobiopsy.The technique was performed through an existing percutaneous transhepatic tract.Multiple specimens were obtained after passing the forceps biopsy into a long 8 French sheath and the specimens were fixed with formalin, and then for histopathologic diagnosis. Results: The histopathologic diagnosis was acquired in 22 of 24 patients, the positive rate was 91.67%(22/24).Pathologic reports included cholangioadenocarcinoma ( n =15),cholangiosquamocarcinoma ( n =1), pancreatic adenocarcinoma ( n =2), hepatoma with common bile duct invasion ( n =2), stomachoadenocarcinoma with common bile duct metastasis ( n =1) and sclerotic cholangitis ( n =1).Conclusion: Percutaneous transhepatic cholangiobiopsy is an accurate and reliable way which is safe and easy to perform to acquire histopathologic diagnosis.
Keywords:bile duct neoplasm  percutaneous transhepatic cholangiography  obstructive jaundicei  bile ducts biopsy  histopathology
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