降钙素原、C反应蛋白与白细胞在诊断小儿呼吸道感染性疾病中的比较

目的：比较小儿呼吸道细菌感染与非细菌感染患儿血清降钙素原（PCT）、C反应蛋白（CRP）及白细胞（WBC）总数水平的不同，探讨PCT、CRP与WBC在细菌感染中的诊断价值。方法：将220例呼吸道感染性疾病患儿，根据有无细菌感染分为细菌感染组142例和非细菌感染组78例，所有患儿分别检测血清PCT、CRP及WBC水平，并对两组患儿的检测结果进行比较。结果：细菌感染组患儿血清PCT、CRP及WBC检测阳性率均高于非细菌感染组，差异均有统计学意义（P〈0．05）；PCT的敏感性、特异性均明显高于CRP和WBC。结论：血清PCT对细菌感染性疾病的诊断价值优于CRP和WBC，是小儿细菌感染的敏感标志物之一。

Procalcitonin,CRP and WBC in Diagnosis of Diseases in Children with Respiratory Tract Infection

Objective：To compare the respiratory tract infection of children with bacterial and non bacterial infections serum proealcitonin （ PCT ）, C reactive protein （ CRP ） and white blood cell （ WBC ） count of different levels, to explore the value of PCT, CRP and WBC in diagnosis of bacterial infection.Me~od ： Two hundred and twenty patients with respiratory tract infection in chiXdren, according to the presence or absence of bacterial infection were divided into bacterial infection group for 142 cases and non bacterial infection group for 48 cases, al｜ patients were detected in the serum PCT, CRP and WBC levels, and the detection results of two groups of children were compared.Result： The serum PCT, CRP and WBC positive rate of bacterial infection group were higher than that of non bacterial infection group, the differences were statistically significant （ P〈0.05 ） ; the sensitivity and the specificity of PCT were significantly higher than those in CRP and WBC.Conclusion： Serum PCT on bacterial infectious disease diagnosis value than CRP and WBC, it is one of the sensitive marker of bacterial infection in children.