抗菌药物专项整治对某三甲医院特殊使用级抗菌药物应用的影响与分析

目的：探讨抗菌药物专项整治对某三甲医院2011—2013年一季度特殊使用级抗菌药物临床应用情况的影响。方法：采用限定日剂量为指标的分析方法，对抗菌药物及特殊使用级抗菌药物的应用数据及相关指标按季度进行统计分析。结果：专项整治后，特殊使用级抗菌药物金额占抗菌药物金额比例从2011年一季度39．76％下降到2013年一季度24．56％，2012年二季度之后抗菌药物使用率均低于60．00％，特殊使用级抗菌药物使用率控制5．40％以下，2012年四季度该院抗菌药物使用强度为每百人天39．8DDDs，该院特殊使用级抗菌药物使用基本合理。结论：抗菌药物专项整治活动取得一定的成效，对该院特殊使用级抗菌药物的合理使用起到了一定的规范作用。

Impact and analysis of the utilization of antibacterial drugs for special use in a first-class hospital with special rectification activities of antibacterials

Objective： To investigate the implementation effect of special rectification activities on use of special level antibacterial drugs in a first-class hospital from 2011 to the first quarter of 2013. Methods： The application of antibacterials and special level antibacterial drugs and relevant indicators were statistically analyzed by the method of defined daily dose （DDD）. Results： Through special rectification activities, the rate of consumption of special level antibacterial drugs in antibacterials amount fell from 39.76% in the first quarter of 2011 to 24.56% in the first quarter of 2013. After the second quarter of 2012, the utilization rate of antibacterials was not more than 60.00%, and the rate of use of special level antibacterial drugs was controlled below 5.40%. The use intensity of antibacterial drugs was 39.8 DDDs per 100 patients in the fourth quarter of 2012. The use of special antibacterial drugs in this hospital was basically rational. Conclusion： Through the special rectification activities, the rational use of special level antibacterial drugs was normalized.