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大骨节病患者软骨中组织蛋白酶D的活性
引用本文:袁素芬 殷培璞. 大骨节病患者软骨中组织蛋白酶D的活性[J]. 中国地方病学杂志, 1989, 8(1): 7-9
作者姓名:袁素芬 殷培璞
作者单位:西安医科大学生化教研室(袁素芬),西安医科大学骨病研究室(殷培璞,郭雄),西安医科大学一附院骨科(邱裕生)
摘    要:
本文测定了大骨节病和非骨关节病患者的关节软骨溶酶体组织蛋白酶 D 活性。结果表明 大骨节病患者组织蛋白酶 D 活性不论是游离型或是酶的总活性均较非骨关节病惠者的酶活性升高,游离型与酶总活性的比值也增大。

关 键 词:组织蛋白酶D  溶酶体  大骨节病  软骨

Activity of cartilage cathepsin D in patient with Kashin-Beck disease
Yuan Sufen,et al. Activity of cartilage cathepsin D in patient with Kashin-Beck disease[J]. Chinese Jouranl of Endemiology, 1989, 8(1): 7-9
Authors:Yuan Sufen  et al
Affiliation:Department of Biochemistry.Xian Medical University
Abstract:
Activity of lysosomal cathepsin D in arthrodial cartilage was determined inpatients with Kashin-Beck disease and non-arthronosos.Results showed that theactivity of cartilage cathepsin D in patient with Kashin Beck disease was higherthan that in patient with non-arthronosos,whether free type or total activity,andthe activity ratio of free type to total activity were increased too.
Keywords:Cathepsin D  Lysosome  Kashin-Beck disease  Cartilage
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