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| 不同NYHA分级慢性心力衰竭患者NT-proBNP的变化及意义 | |
| 引用本文： | 孙晶,王玲. 不同NYHA分级慢性心力衰竭患者NT-proBNP的变化及意义[J]. 疾病监测与控制, 2011, 0(12): 716-718 |
| 作者姓名： | 孙晶 王玲 |
| 作者单位： | 内蒙古自治区医院心内科,内蒙古呼和浩特010017 |
| 摘 要： | 目的探讨血浆NT-proBNP（氮端前体脑钠肽）浓度变化在慢性心衰患者中的意义。方法选择慢性心力衰竭患者65例,NYHA分级分为Ⅱ-Ⅳ级,正常对照组21例,测定NT-proBNP血浆浓度。结果各组间NT-proBNP差别有统计学意义（P〈0.01）,NT-proBNP与NYHA分级呈正相关（r=0.509,P〈0.01）,抗心衰治疗7天后,与入院时相比各心衰组NT-proBNP明显下降（P〈0.01）。结论监测NT-proBNP,对慢性心衰的诊断、严重程度的判断、疗效判定是一项快速简便的指标,值得广泛应用于临床心力衰竭患者。 |
| 关 键 词： | 氮端前体脑钠肽 心力衰竭 NYHA分级 |
The changes and significance of NT-proBNP inDifferent NYHA class patients with chronic heart failure |
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| SUN Jing,WANG ling. The changes and significance of NT-proBNP inDifferent NYHA class patients with chronic heart failure[J]. , 2011, 0(12): 716-718 | |
| Authors: | SUN Jing WANG ling |
| Affiliation: | (Inner Mongolia Autonomous Region Hospital,Hohhot 010017,China) |
| Abstract: | Objective Study the significance of plasma NT-proBNP changes in patients with chronic heart failure.Methods Select 65 cases with chronic heart failure,divided them intoⅡ-Ⅳclass by NYHA class,21 cases without heart failure were included as the control group.Determine their NT-proBNP plasma concentration.Results The differences of NT-proBNP in different group were significant（P0.01）;NT-proBNP showed positive correlation with NYHA class（r = 0.509,P0.01）;After 7days＇Anti-heart failure therapy,compared to the admission the NT-proBNP in each NYHA class decreased significantly（P0.01）.Conclusion Monitoring NT-proBNP is a quick and easy evaluation on diagnosing accuratly,judging the severity and determing the efficacy of chronic heart failure.It should widely used in clinical heart failure patients. |
| Keywords: | NT-proBNP heart failure NYHA class |
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