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Stenting and interventional radiology for obstructive jaundice in patients with unresectable biliary tract carcinomas
Authors:Toshio Tsuyuguchi  Tadahiro Takada  Masaru Miyazaki  Shuichi Miyakawa  Kazuhiro Tsukada  Masato Nagino  Satoshi Kondo  Junji Furuse  Hiroya Saito  Masafumi Suyama  Fumio Kimura  Hideyuki Yoshitomi  Satoshi Nozawa  Masahiro Yoshida  Keita Wada  Hodaka Amano  Fumihiko Miura
Affiliation:1. Department of Medicine and Clinical Oncology, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-0856, Japan
2. Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan
3. Department of General Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
4. Department of Gastroenterological Surgery, Fujita Health University, Toyoake, Japan
5. Department of Surgery and Science, Graduate School of Medicine and Pharmaceutical Science for Research, University of Toyama, Toyama, Japan
6. Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
7. Department of Surgical Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
8. Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital East, Chiba, Japan
9. Department of Radiology, Asahikawa Kosei General Hospital, Asahikawa, Japan
10. Department of Gastroenterology, Juntendo University, Tokyo, Japan
Abstract:Together with biliary drainage, which is an appropriate procedure for unresectable biliary cancer, biliary stent placement is used to improve symptoms associated with jaundice. Owing to investigations comparing percutaneous transhepatic biliary drainage (PTBD), surgical drainage, and endoscopic drainage, many types of stents are now available that can be placed endoscopically. The stents used are classified roughly as plastic stents and metal stents. Compared with plastic stents, metal stents are of large diameter, and have long-term patency (although they are expensive). For this reason, the use of metal stents is preferred for patients who are expected to survive for more than 6 months, whereas for patients who are likely to survive for less than 6 months, the use of plastic stents is not considered to be improper. Obstruction in a metal stent is caused by a tumor that grows within the stent through the mesh interstices. To overcome such problems, a covered metal stent was developed, and these stents are now used in patients with malignant distal biliary obstruction. However, this type of stent has been reported to have several shortcomings, such as being associated with the development of acute cholecystitis and stent migration. In spite of these shortcomings, evidence is expected to demonstrate its superiority over other types of stent.
Keywords:biliary stenting  biliary tract cancer  obstructive jaundice  guidelines
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