A new prenylated dihydrochalcone from the leaves of Artocarpus lowii |
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| Authors: | Shajarahtunnur Jamil Hasnah Mohd Sirat Ibrahim Jantan Norio Aimi Mariko Kitajima |
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| Affiliation: | (1) Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, UTM Skudai, 81310 Johor Bahru, Johor, Malaysia;(2) Department of Pharmacy, Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia;(3) Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan |
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| Abstract: | A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy-3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1–3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1–3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry. |
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| Keywords: | Artocarpus lowii Moraceae Leaves Chalcone Antioxidant DPPH ESR |
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