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| Morphologic damage of neurons in hippocampus （CA－1） following focal brain cortex contusion： a quantitative histopathologic st | |
| 引用本文： | 张剑宁,易声禹,章翔,上官学芬. Morphologic damage of neurons in hippocampus （CA－1） following focal brain cortex contusion： a quantitative histopathologic st[J]. 中国人民解放军军医大学学报, 1995, 0(4) |
| 作者姓名： | 张剑宁 易声禹 章翔 上官学芬 |
| 作者单位： | Zhang Jianning;Yi Shengyu; Zhang Xiang; Shangguan Xuefen(Department of Neurosurgery，Xijing Hospital，Fourth Military Medical University，Xi'an，710032)(Department of Pathology，Fourth Military Medical University，Xi'an，710032) |
| 摘 要： | Ｍｏｒｐｈｏｌｏｇｉｃｄａｍａｇｅｏｆｎｅｕｒｏｎｓｉｎｈｉｐｐｏｃａｍｐｕｓ（ＣＡ－１）ｆｏｌｌｏｗｉｎｇｆｏｃａｌｂｒａｉｎｃｏｒｔｅｘｃｏｎｔｕｓｉｏｎ：ａｑｕａｎｔｉｔａｔｉｖｅｈｉｓｔｏｐａｔｈｏｌｏｇｉｃｓｔｕｄｙ￥ＺｈａｎｇＪｉａｎｎｉ... |
Morphologic damage of neurons in hippocampus (CA-1) following focal brain cortex contusion:a quantitative histopathologic study |
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| Zhang Jianning,Yi Shengyu, Zhang Xiang, Shangguan Xuefen. Morphologic damage of neurons in hippocampus (CA-1) following focal brain cortex contusion:a quantitative histopathologic study[J]. Journal of Medical Colleges of PLA(China), 1995, 0(4) | |
| Authors: | Zhang Jianning Yi Shengyu Zhang Xiang Shangguan Xuefen |
| Abstract: | The present study was designed to investigate the hippocampus injury in response to focal brain trauma. Neuron damage in the cortex and the hippocampus (CA-1) was assessed quantitatively with light microscope through a cerebral contusion model of rat. The necrotic neuron in hippocampus regestered 36.70% 6 h after injury and increased to 77. 85% 24 h following trauma. However, no additional damage was observed 72 and 168 hours after trauma. The results suggest that the characteristic injury in the hippocampus (CA-1) may constitute an important pathological factor contributing to hypomnesia and learning disorder following the brain trauma. |
| Keywords: | brain injuries hippocampus pathology |
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