Light and electron microscopic findings in eyelid tumors after cryotherapy

Over the past five years 112 patients underwent cryotherapy of lid tumours. Two methods of freezing, contact freezing and spray freezing, were used. Biopsy specimens for histological studies were taken before and after cryotherapy. The results of light and electron microscopy are reported. Electron microscopic examination shows that cryonecrosis exhibits the well known general characteristics of necrosis. Cryotherapy results in extensive tumour necroses and this fact explains the success rate of 90.9% in basalioma 5 years after therapy.