前列腺特异性抗原（PSA）定量检测在前列腺疾病中的诊断价值

目的探讨前列腺特异性抗原（PSA）定量检测在前列腺疾病的诊断、鉴别诊断以及预后监测等方面的临床价值。方法前列腺癌26例,前列腺增生症65例,前列腺炎29例,非前列腺疾病23例,正常男性100例,于早晨空腹采静脉血3ml,用全自动化学发光免疫分析仪（ACCESS2）进行PSA定量测定。结果前列腺癌组PSA值78.42±11.69ng/ml,显著高于前列腺增生症组、前列腺炎组、非前列腺疾病组及正常男性对照组PSA值（P〈0.01）。结论 PSA可作为早期诊断前列腺癌的灵敏肿瘤标记物和前列腺疾病疗效监测的有价值指标。

Diagnostic Value of Quantitative Detection of Prostate-specific Antigen in Prostate Diseases

Objective To study the clinical value of quantitative detection of prostate-specific antigen（PSA） in diagnosis,differential diagnosis,and prognosis monitoring of prostate diseases.Methods 3ml blood samples were collected from 26 cases of patients with prostate cancer,65 cases of patients with benign prostatic hyperplasia,29 cases of patient with prostatitis,23 cases of patient without prostate disease,and 100 cases of normal male people on an empty stomach in the morning,respectively and PSA was detected quantitatively with automated chemiluminescent immunoassay analyzer（ACCESS2）.Results PSA value was 14.54ng/ml in prostate cancer group and（2.10~10.61）ng/ml in benign prostatic hyperplasia group.The PSA value was in the normal range for prostatitis group,non-prostate disease and the normal group.Conclusion PSA can be used as early diagnosis of prostate cancer,and it is a sensitive index for tumor marker and prognosis monitoring of prostate diseases.