活体肝移植小肝综合征的研究进展

目的 探讨在活体肝移植中小肝综合征发生的原因、预防及治疗方法.方法 复习国内、外近几年活体肝移植术后有关小肝综合征的相关报道.结果 供体年龄、脂肪肝程度、受体术前疾病状态(MELD评分)、术后高门静脉灌注、流出道不畅及移植物大小和质量对活体肝移植术后小肝综合征的发生起着重要作用,术前选择最佳的供体,术中的脾脏切除或脾动脉结扎或对门静脉限流,保证流出道的绝对通畅,术后及早发现并积极治疗能显著减少小肝综合征的发生.结论 小肝综合征的危险因素是可以预测的,积极的应对措施可以用于小肝综合征的预防与治疗.

Advances in Small-for-Size Syndrome in Living Donor Liver Transplantation

Objective To review the causes,prevention methods,and therapies of the small-for-size syndrome(SFSS) in living donor liver transplantation(LDLT).Methods The literatures about SFSS in recent years were reviewed and summarized.Results The donor's age,graft steatosis level,MELD score of the recipient,portal hypertension,low outflow,and graft size were risk factors of SFSS.Ideal donor,splenectomy,ligating splenic artery,keeping a satisfactory intraoperative outflow,early diagnosis and active therapy could obvio...