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| 雷公藤中木脂素类成分的研究 | |
| 引用本文： | 林绥,李援朝,刘子皎,邓福孝. 雷公藤中木脂素类成分的研究[J]. 中国药学杂志, 2000, 35(4): 231-232 |
| 作者姓名： | 林绥 李援朝 刘子皎 邓福孝 |
| 作者单位： | 1. 福州 350001 福建省医学科学研究所 2. 上海 200031 中国科学院上海药物研究所 |
| 摘 要： | 目的：对雷公藤(Tripterygium wilfardine Hook.f.)的化学成分进行分离鉴定。方法：以乙醇渗渡提取，硅胶柱层析分离，理化常数和光谱数据确定3个化合物的结构。结果：分得3个化合物，分别鉴定为：①木脂素类化合物：Ⅰ：5ˊ-甲氧基-(一)-松脂素(medioresinol)；Ⅱ：丁香脂素(syringaresinol)；②降倍半萜内酯：Ⅲ：雷藤素(wilforonide)。结论：化合物Ⅰ和Ⅱ为首次从雷公藤中获得。 |
| 关 键 词： | 雷公藤 木脂素类化合物 雷藤素 |
| 收稿时间： | 1999-08-18; |
Studies on lignans constituents of Tripterygium Wilfordine |
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| Lin Sui. Studies on lignans constituents of Tripterygium Wilfordine[J]. Chinese Pharmaceutical Journal, 2000, 35(4): 231-232 | |
| Authors: | Lin Sui |
| Affiliation: | (Lin S),Li Yuanchao (Li YC),Liu Zijiao (Liu ZJ |
| Abstract: | OBJECTIVE:To study the chemical constituents of roots of Tripterygium wilfordine Hook .f. METHODS: Lignans compounds were extracted and separated by means of cool ethanol extraction and chromatography on silica gel.Their structures were determined by physical,chemical and spectral data analysis. RESULTS: Three compounds were isolated from ethanol extracts:①Lignans compounds:Ⅰ:medioresinol；Ⅱ:syringaresinol;②sesquierpene olide:Ⅲ:wilforonide. CONCLUSION: CompoundⅠ,Ⅱ were separated from Tripterygium wilfordine Hook .f. for the first time. |
| Keywords: | Tripterygium Wilfordine lignans compounds wilforonide |
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