半侧面肌痉挛的诊断和治疗

目的　观察半侧面肌痉挛患者的临床表现和肉毒毒素对半侧面肌痉挛的治疗效果。方法　对近 3年来神经内科门诊诊断的面肌痉挛病人 2 90例进行回顾性研究 ,使用 Cohen's量表对治疗效果进行评估。结果　治疗后起效时间是 5 .4± 7.8天 ,效果持续 18.4± 6 .1周。治疗后完全缓解率达 83.8% ,明显缓解率达 15 .2 %。 30 %的患者有副作用 ,主要是面肌、眼睑无力 ,眼睑下垂 ,流泪和眼干及复视 ,但这是暂时的、可逆的 ,2周内基本消失。结论　 A型肉毒毒素治疗方法简便、易行 ,是治疗面肌痉挛的首选药物

Diagnosis and treatment of hemifacial spasm

Objective　To observe clinical feature of patients with hemifacial spasm and therapeutic effect of Chinese botulinum toxin type A.Methods　We followed up 29 cases with hemifacial spasm for 3～13 months after treatment and valued the therapeutic effect using Cohen's scales for them.Results　83.8% of the patients had completed remission,15.2% obvious improvement.The effect lasted 18.4±6.1 weeks,30% of the patients had mild unwanted effect including weakness of facial muscles and eyelid、ptosis、eye dry and blurred vision.All have recovered within two weeks.Conclusions　Chinese botulinum toxin type A appears an effective and safe treatment for hemifacial spasm.