卵巢早衰病因学研究进展

卵巢早衰是一种多病因引起的妇科内分泌疾患,在人群中的发生率为1％-3％。有许多因素与之相关,如自身免疫因素、细胞与分子遗传性因素、代谢因素、理化药物及感染因素等。对其病因学的研究,旨在指导临床预防和治疗,提高生育力,缓解低雌激素水平所致的并发症。

Progress of Premature Ovarian Failure Etiological Studying

Premature ovarian failure (POF) is a unique example of isolated female organ senescence, with a population prevalence of approximately 1%-3%. Through the phenotypic expression of POF is similar to that of age-appropriate natural menopause, the underlying etiology mechanisms are diverse and not entirely clear, ranging from autoimmune factor, cellular and molecular genetics factor, metabolism factor, physical and chemical factor to infectious factor. The researches on the etiology aim at guiding clinical prevention and treatment, improving fertility and alleviating the complications that the low estrogen level causes.