| 严重烫伤大鼠肠粘膜通透性改变及其机理 |
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| 引用本文： | 余佩武,肖光夏,府伟灵,周立新,秦孝健. 严重烫伤大鼠肠粘膜通透性改变及其机理[J]. 中华烧伤杂志, 1996, 0(5) |
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| 作者姓名： | 余佩武 肖光夏 府伟灵 周立新 秦孝健 |
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| 作者单位： | 西南医院普外科，第三军医大学西南医院烧伤研究所，第三军医大学西南医院烧伤研究所，第三军医大学西南医院烧伤研究所，第三军医大学西南医院烧伤研究所 重庆630038，重庆630038，重庆630038，重庆630038 |
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| 摘 要： | ![]()
采用~(99m)Tc-DTPA 血至肠腔清除率定量测定方法,观察大鼠严重烫伤后肠粘膜通透性的变化规律及血小板活化因子(PAF)对其产生的影响,以探讨严重烫伤后肠粘膜屏障功能损害的病理生理过程及机理。结果表明:严重烫伤后肠粘膜通透性显著升高,与肠组织 PAF 含量升高呈显著正相关(r=0.94,P<0.01),PAF 拮抗剂治疗能明显降低肠粘膜通透性。提示,PAF 是导致严重烫伤后肠粘膜通透性升高的重要因素之一。
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| 关 键 词： | 烧伤 肠通透性 血小板活化因子 |
A study on changes and its mechanisms of intestinal mucosal permeability after severe burn |
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| Yu Peiwu Xiao Guangxia Fu Weiling Burn Research Institute,Southwest Hospital,Third Military Medical College,Chongqing. A study on changes and its mechanisms of intestinal mucosal permeability after severe burn[J]. Chinese journal of burns, 1996, 0(5) |
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| Authors: | Yu Peiwu Xiao Guangxia Fu Weiling Burn Research Institute Southwest Hospital Third Military Medical College Chongqing |
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| Affiliation: | Yu Peiwu Xiao Guangxia Fu Weiling Burn Research Institute,Southwest Hospital,Third Military Medical College,Chongqing 630038 |
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| Abstract: | ![]()
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| Keywords: | Burn Intestinal permeability Plateletactivating factor |
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