三维适形放射治疗局限性骨转移癌的止痛效果

目的:分析三维适形放射治疗对局限性骨转移癌的止痛作用方法:全组52例,年龄48~75岁。非小细胞肺癌17例、乳腺癌15例、前列腺癌和肾癌各6例,直肠癌5例和3例为甲状腺癌转移。采用三维适形放疗,根据CT显示病变范围设定临床靶区,设5~6个共面照射野,根据剂量分布决定每个照射野的权重。中位剂量40Gy/8次,(平均35Gy-45Gy/7-10次)。治疗期间配合适量激素。结果:止痛效果明显,总有效率达100%。截止2007年2月,有随访结果的38例,其中18例生存1年,9例存活2年,6例存活3年,有5例存活4年健在。结论:三维适形照射技术对局限性骨转移癌不仅有肯定的止痛效果,而且对控制病变的发展同样是一种较为理想的治疗方法。

RESULT OF THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY FOR LIMITATION BONE METASTATIC CANCER IN PAIN ALLEVIATION

Objective: To analyze the effect of three-dimensional conformal radiotherapy on bone metastatic cancer pain alleviation.Methods: 52 cases aged from 48 to 75,including 17 cases of non-small cell lung cancer,15 cases of breast cancer,6 cases of prostate and kidney cancer,rectum cancer 5 cases and thyroid cancer 3 cases.Three-dimensional conformal radiotherapy was used to treat the patients with a median dose of 40 Gy/8 times(35Gy-45Gy)/7-10 frequency.Results: Pain relief rate was 100%.Till February 2007,among the 38 follow-up patients,18 cases survived 1 year,9 cases survived 2 years,6 cases survived 3 years and 5 cases survived 4 years and still alive.Conclusion: Three-dimensional conformal radiotherapy is an effective treatment method for bone metastatic cancer.