幽门螺杆菌感染与非甾体类抗炎药相关性初探

目的 探讨幽门螺杆菌感染与非甾体类抗炎药的关系。方法 将本院2004年1月至2005年12月期间收治的88例连续服用非甾体类抗炎药治疗4～12周的患者行胃镜及病理组织学检查，经检查将88例患者分为幽门螺杆菌感染组和非感染组，分析非甾体类抗炎药与幽门螺杆菌感染的关系。结果 幽门螺杆菌感染组36例，非甾体类抗炎药相关性胃病发生率16．67％（6／36），非幽门螺杆菌感染组52例，非甾体类抗炎药相关性胃病发生率19．23％（10／52）。结论 幽门螺杆菌感染并不加剧非甾体类抗炎药相关性胃病的发生。

The correlative study on helicobacter pylori and non-steroidal anti-inflammatory drugs

Objective To assess the relationship between helicobacter pylori infection and the incidence of di- gestive disease associated with NSAIDs.Methods 88 patients who had taken NSAIDs undergoing endoscopy were selected.The patients were assigned into two groups:helicohacter pylori infection group and no-hslicobacter pylori group.Results Digestive disease associated with NSAIDs occurred in 16.67% of patients with helicobacter pylori infection compared with 19.23% in no-helicobacter pylori group.There was no significant difference in statistical analysis.Conclusion Helicobacter pylori infection dosen't aggravate digestive disease associated with NSAIDs.