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Maternal sleep duration and complaints of vital exhaustion during pregnancy is associated with placental abruption |
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| Authors: | Chunfang Qiu Sixto E. Sanchez Bizu Gelaye Daniel A. Enquobahrie Cande V. Ananth Michelle A. Williams |
| Affiliation: | 1. Swedish Medical Center, Center for Perinatal Studies, Seattle, WA, USA,;2. Department of Obstetrics and Gynecology, San Martin de Porres University, Lima, Peru,;3. Asociación Civil PROESA, Lima, Peru,;4. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA,;5. Swedish Medical Center, Center for Perinatal Studies, Seattle, WA, USA,;6. Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA,;7. Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY, USA, and;8. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA |
| Abstract: | Objective: Sleep disorders are associated with cardiovascular complications and preterm delivery (PTD). Insufficient sleep results in metabolic alterations and increased inflammation, both known to contribute to placental abruption (abruption), a determinant of PTD. We examined associations of abruption with sleep duration and complaints of vital exhaustion. Methods: The study included 164 abruption cases and 160 controls in a multicenter study in Peru. Data on habitual sleep duration and vital exhaustion during the first 6 months of pregnancy were elicited during interviews conducted following delivery. Women were categorized according to short, normal and long sleep duration (≤6, 7–8 and ≥9?h); and frequency of feeling exhausted. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. Results: Short and long sleep durations were associated with increased odds of abruption. The ORs of abruption in relation to short (≤6?h) and long (≥9?h) sleep duration were 2.0 (95% CI 1.1–3.7) and 2.1 (95% CI 1.1–4.1), compared with normal sleep duration (7–8?h). Complaints of vital exhaustion were also associated with abruption (OR?=?2.37; 95% CI 1.46–3.85), and were independent of sleep duration. Conclusion: We extend the existing literature and support the thesis that maternal sleep habits and disorders should be assessed among pregnant women. |
| Keywords: | Exhaustion placental abruption pregnancy sleep duration |