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正交设计试验法优选淫羊藿提取工艺条件
引用本文:王洪锐,杨帆,陈健勇,谭新,梁惠明.正交设计试验法优选淫羊藿提取工艺条件[J].广东药学院学报,2003,19(1):7-8.
作者姓名:王洪锐  杨帆  陈健勇  谭新  梁惠明
作者单位:1. 深圳宝安石岩人民医院药剂科,广东,深圳,518000
2. 广东药学院药剂学教研室,广东,广州,510224
3. 广东药学院99级学生
基金项目:广东省中医药管理局基金资助项目 (No .10 2 0 82 )
摘    要:目的:优化乙醇回流法提取淫羊藿的工艺条件。方法:以淫羊藿苷的含量为指标,通过正交设计试验筛选乙醇回流法提取淫羊藿的最佳提取工艺,结果:影响淫羊藿乙醇回流法提取的主次因素为:溶媒用量>乙醇浓度>提取次数>提取时间,最佳提取工艺条件是:用8倍80%的乙醇回流,提取3次,每次30min,结论:通过正交设计试验优选得到的淫羊 藿乙醇回流法的提取工艺条件稳定可行。

关 键 词:淫羊藿  乙醇回流法  提取工艺
文章编号:1006-8783(2003)01-0007-02
修稿时间:2002年12月2日

Optimization of the extraction process of Herba Epimedii by orthogonal design
WANG Hong rui ,YANG Fan ,CHEN Jian yong ,TAN Xin ,LIANG Hui ming.Optimization of the extraction process of Herba Epimedii by orthogonal design[J].Academic Journal of Guangdong College of Pharmacy,2003,19(1):7-8.
Authors:WANG Hong rui  YANG Fan  CHEN Jian yong  TAN Xin  LIANG Hui ming
Institution:WANG Hong rui 1,YANG Fan 2,CHEN Jian yong **,TAN Xin **,LIANG Hui ming **
Abstract:Objective: To optimize the ethanol refluxing and extracting process of Herba Epimedii with orthogonal design. Methods: The optimum extraction conditions were investigated by orthogonal design and with Icariin as the content index. Results: The factors influencing extraction efficiency were as follows: the amount of ethanol > the concentration of ethanol > times of extraction > duration of extraction. The optimum extraction condition obtained was: 80% ethanol,with the volume of 8 folds of Epimedii ,refluxing and extracting for 3 times,30 mins for every turn. Conclusion: The optimized process is feasible for the extraction of Herba Epimedii.
Keywords:Herba Epimedii  ethanol refluxing process  extraction
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