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脾虚与胃黏膜防御机制相关性的研究进展及评价
引用本文:王晓娜,朱方石. 脾虚与胃黏膜防御机制相关性的研究进展及评价[J]. 辽宁中医杂志, 2010, 0(6): 1176-1179
作者姓名:王晓娜  朱方石
作者单位:[1]南京中医药大学,江苏南京210028 [2]南京中医药大学附属中西医结合医院,江苏南京210028
基金项目:“十一五”国家科技支撑计划资助项目(2007BAI20B093)
摘    要:就脾虚与胃黏膜防御机制的相关性从胃黏膜等组织中NO含量、胃黏膜免疫机制、胃泌素、表皮生长因子、胃黏膜血流量等5个方面进行了综述,普遍认为脾虚与胃黏膜免疫机制下降、胃黏膜等组织中NO含量变化、胃泌素分泌异常、EGF的表达变化以及胃黏膜血流降低等因素相关,胃黏膜防御机制功能的降低贯穿在中医脾虚的病理过程和病理证候之中;同时,就脾虚与胃黏膜防御机制相关性研究中存在的不足进行了评价,提出了展望。

关 键 词:胃黏膜防御机制  脾虚  综述

The Progress and Evaluation on Studies of Correlation Between Spleen Deficiency and Gastric Mucosa Defense Mechanism
WANG Xiao-na,ZHU Fang-shi. The Progress and Evaluation on Studies of Correlation Between Spleen Deficiency and Gastric Mucosa Defense Mechanism[J]. Liaoning Journal of Traditional Chinese Medicine, 2010, 0(6): 1176-1179
Authors:WANG Xiao-na  ZHU Fang-shi
Affiliation:1.Nanjing University of Traditional Chinese Medicine,Najing 210028,Jiangsu,China;2.Academy of Traditional Chinese Medicine of Jiangsu Province,Nanjing,210028,Jiangsu,China)
Abstract:This paper takes Summary in every way of correlation between spleen deficiency and Gastric mucosa defense mechanism from the content of gastric mucosa tissue NO,Gastric mucosal immunity Mechanism,Gastrin,EGF,Gastric mucosal blood flow.It is thought that spleen deficiency is related to the following factors: gastric mucosal immunity mechanism,content changes of gastric mucosa tissue NO,abnormity of gastrin secretion,EGF expression,reduction of gastric mucosal blood flow.And the depressed gastric mucosal defense mechanism is thought to play a role in the whole pathological process of the spleen deficiency,and be related to all kinds of pathological syndrome of spleen deficiency.while,the deficiency of the research gaps have been evaluated and presented.
Keywords:Gastric mucosa defense mechanism  spleen deficiency  Summary
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