原发性肺淋巴瘤三例报道并文献复习

目的探讨原发性肺淋巴瘤的临床特点、诊断和治疗方法。方法回顾性总结原发性肺淋巴瘤3例,并结合文献对其临床表现、影像学特点、诊断及治疗方法进行分析。结果原发性肺淋巴瘤罕见,无特异性临床表现和影像学改变,易误诊。其主要症状为咳嗽、发热等。影像学可表现为单发或多发结节或片状影甚至实变,常见有充气支气管征。确诊依靠开胸手术、胸腔镜或经皮肺穿刺获取组织,结合病理学和免疫组化检查。主要治疗手段为化疗。结论及时进行有创检查有利于早期诊断原发性肺淋巴瘤。

Three Cases of Primary Pulmonary Lymphoma and Review of the Literature

Objective To study the clinical characteristics, diagnosis and treatment of primary pulmonary lymphoma. Methods A retrospective review of primary pulmonary lymphoma cases at a single institution from 2006 to 2008 was performed, and relevant literature was reviewed. Results Primary pulmonary lymphoma is a rare disease. The diagnosis was difficult because of the lack of specific characteristics. The most common symptoms were cough and fever. X-ray feature included solitary or multiple nodules and consolidation. Definite diagnosis was made by pathologic and immunohistchemieal examinations. The recommended first-line therapy is chemotherapy. Conclusion Appropriate invasive biopsy is necessary for early diagnosis of primary pulmonary lymphoma.