正常妊娠妇女不同孕期血常规参数变化的研究

目的对不同孕期的妊娠妇女血常规检测结果进行分析,为临床诊断建立参考区间提供实验室数据。方法将3 222例正常妊娠妇女按照孕周不同分为孕早期、孕中期和孕晚期,分别对3个孕期的孕妇进行红细胞(RBC)、血红蛋白(Hb)、血细胞比容(HCT)、白细胞(WBC)、中性粒细胞百分比(N%)、淋巴细胞百分比(L%)的测定和统计分析,并与作为对照组的355例非孕健康育龄妇女的相应检测项目进行比较。结果正常妊娠者在不同孕期RBC、Hb、HCT水平均比对照组妇女低,在孕中期下降达孕期最低水平(P0.05),不同孕期之间比较差异有统计学意义(P0.05)。正常妊娠者WBC、N%均比对照组高,而L%则比对照组低(P0.05)。不同孕期之间WBC参数比较差异也有统计学意义(P0.05)。正常妊娠者血小板(PLT)计数较对照组降低,正常妊娠者在孕晚期达到最低值(P0.05)。结论建立正常妊娠妇女的血常规参数参考区间,有利于对妊娠贫血、感染、妊娠高血压综合征等疾病的诊断。

Changes of parameters in blood routine tests for normal pregnant women

Objective To observe the parameters of venous blood cells in normal pregnant women and analyze the normal level range in different gestation period .Methods The parameters of venous blood cells of 3 222 pregnant women in early ,middle and late gestational period and 355 normal non‐pregnant women as the control were measured by automatic blood cell analyzer ,including red blood cell(RBC) ,hemoglobin(Hb) ,hematocrit(HCT ) ,white blood cell(WBC) ,percentage of neutrophils(N% ) and Lympho‐cyte(L% ) .Results RBC ,Hb and HCT in normal pregnancy group in different gestational weeks was lower than that in normal non‐pregnant women(P<0 .05) .The lowest values of RBC ,Hb and HCT appeared in the middle gestational stage(P< 0 .05) . There were differences among different gestational stages(P<0 .05) .WBC and N% in the normal pregnancy group increased while L% decreased compared with the non‐pregnant group in different gestational stages .There was significantly statistical difference a‐mong different gestational stages(P<0 .05) .PLT in normal pregnant women gradually decreased compared with the non‐pregnant women ,and the lowest values of PLT appeared in the later gestational stage(P<0 .05) .Conclusion It is necessary to build the ref‐erence value of blood cell parameters in normal pregnant women of different gestation period which is beneficial to the diagnosis of diseases such as anemia ,infection and hypertension syndrome induced by pregnancy .