| 冠心病患者血清补体C1q水平变化及其临床意义 |
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| 引用本文： | 辛娜,吴跃刚,王瑶,邓克廷,王永锋. 冠心病患者血清补体C1q水平变化及其临床意义[J]. 检验医学与临床, 2016, 0(20). DOI: 10.3969/j.issn.1672-9455.2016.20.020 |
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| 作者姓名： | 辛娜 吴跃刚 王瑶 邓克廷 王永锋 |
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| 作者单位： | 1. 西安医学院第一附属医院检验科,陕西西安,710077;2. 陕西省西安市华山中心医院内科 710043 |
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| 摘 要： | 目的探讨冠状动脉粥样硬化性心脏病(CHD)患者血清补体C1q水平变化及其临床意义。方法于2015年10月至2016年3月,选择住院治疗CHD患者92例,根据临床类型分为稳定性心绞痛(SAP)组和急性冠脉综合征(ACS)组。以同期体检健康者50例作为对照组。检测各组受试者血清C1q水平。结果 ACS组血清C1q水平高于对照组和SAP组(P0.05),SAP组与对照组C1q水平比较差异无统计学意义(P0.05)。结论 CHD患者血清C1q水平变化与病情进展相关,检测血清C1q有助于判断患者病情及指导临床治疗。
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| 关 键 词： | 补体 C1q 冠心病 急性冠脉综合征 |
Changes and clinical significance of serum complement C1q level in patients with coronary heart disease |
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| Abstract: | Objective To study the changes and clinical significance of serum complement C1q level in patients with coronary heart disease(CHD) .Methods From Oct .2015 to Mar .2016 ,92 CHD patients were enrolled ,and divided into stable angina pecto‐ris(SAP) group and acute coronary syndrome(ACS) group according to the clinical condition .Another 50 healthy subjects were en‐rolled as control group .Serum concentrations of C1q were measured in all groups .Results Serum concentrations of C1q in ACS group was higher than control group and SAP group(P<0 .05) .There was not significantly difference of serum concentrations of C1q between SAP group and control group(P>0 .05) .Conclusion Serum C1q level could be associate with the progression of CHD disease ,and detection of serum C1q might be helpful for judging patients′condition and guiding treatment . |
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| Keywords: | complement C1q coronary heart disease acute coronary syndrome |
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