绝经后出血338例临床与病理分析

目的:分析绝经后出血的原因。方法: 对338例绝经后出血的患者进行临床及病理生理检查, 对结果进行统计学处理和分析。结果: 良性疾病引起的绝经后出血占40 .24%, 非器质性疾病占34 .02%, 恶性肿瘤占25. 74%。子宫内膜病理检查显示萎缩性内膜占44 .93%, 其次为增生、癌性内膜。结论: 出血来自子宫最多见; 恶性肿瘤以子宫内膜癌和宫颈癌为主;出血年龄大, 距绝经的年限长或子宫增大者, 恶性肿瘤的发生率高; 出血多与子宫内膜受卵巢或异源性性激素刺激, 使内膜局部充血或血管病变有关。

Clinical and pathological analysis on 338 cases of postmenopausal uterine hemorrhage

Objective:To analyze the cause of postmenopausal uterine hemorrhage.Methods:338 patients with postmenopausal uterine hemorrhage accepted clinical and pathological examinations were analyzed.Results:Postmenopausal hemorrhage induced by benign diseases accounted for 40.24%, non-organic diseases 34.02% and malignancy 25.74%. Endometrium pathological examination showed that atrophic endometrium accounted for 44.93%, followed by hyperplasia and carcinoma. Conclusion:Most of hemorrhage from uterus, malignancy mainly included endometrial and cervical carcinoma; women with high age and bigger gap to menopause age or uterus augmentation had higher incidence of malignancy. Hemorrhage volume should be related to endometrium congestion or pathological changes in vascular resulting from endometrium stimulated by ovarian or others sexual hormones.