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Surgical significance of mediastinal metastases in lung cancer
Affiliation:1. Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan;2. Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan;3. Department of Thoracic Surgery, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan;4. Department of Thoracic Surgery, Shinkoga Hospital, Fukuoka, Japan;5. Division of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan;6. Niigata Association of Occupational Health, Niigata, Japan;7. Department of General Thoracic Surgery, Southern Tohoku General Hospital, Research Institute for Neuroscience & Respirology, Koriyama, Japan;1. Section of Thoracic Imaging, Department of Diagnostic Radiology, Veterans Affairs Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Building 500, Los Angeles, CA 90073, USA;2. David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA;3. Section of Cardiothoracic Imaging, Radiology Service, Veterans Affairs Palo Alto Healthcare System, 3801 Miranda Avenue, Palo Alto, CA 94304, USA;4. Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1478, Houston, TX 77030, USA;1. Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan;2. Division of General Thoracic Surgery, Kyorin University School of Medicine, Tokyo, Japan
Abstract:Although the spread of tumors is of common concern to both surgeons and pathologists, yet there are indications that in the field of lung cancer metastasis, pathologic and surgical concepts are not yet complementary. A detailed study has, therefore, been made of the topographic distribution of mediastinal lymph node metastases in 100 autopsy cases of lung cancer. Eighty-four per cent showed metastases which were either wholly ipsilateral or larger ipsilaterally. In contrast, 13 per cent displayed metastases which were either equal on both sides or larger contralaterally. The remaining 3 per cent exhibited no discernible metastases. It is concluded that these metastatic patterns accord with the concept that, if the patient's respiratory reserves are adequate, it is rational to resect the lymphatics of the hemithorax radically.
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