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| 男性肥胖骨质疏松患者性激素与骨代谢水平及相关性分析 | |
| 引用本文： | 吕涛,于智君,张媛. 男性肥胖骨质疏松患者性激素与骨代谢水平及相关性分析[J]. 昆明医学院学报, 2014, 35(6): 94-96,100 |
| 作者姓名： | 吕涛 于智君 张媛 |
| 作者单位： | 吕涛(西安交通大学医学院附属红会医院检验科,陕西西安,710054)； 于智君 (西安市第八医院检验科,陕西西安,710061)； 张媛 (西安市第四医院检验科,陕西西安,710004)； |
| 基金项目： | 陕西省科技攻关基金资助项目(项目编号：06K11-G4) |
| 摘 要： | 目的 探讨男性肥胖骨质疏松患者性激素与骨代谢水平及相关性分析.方法 选择男性骨质疏松患者76例,其中肥胖合并骨质疏松39例（A组）、单纯骨质疏松37例（B组）,另选择健康男性40例作为对照组（C组）.分别检查3组患者骨代谢指标、血脂及性激素.结果 A组CTX-1、BGP较B、C组差异有统计学意义（P＜0.05）,B组CTX-1、BGP较C组差异有统计学意义（P＜0.05）.A组TG、TC、HDL、LDL较B、C组差异有统计学意义（P＜0.05）,B组LDL较C组差异有统计学意义（P＜0.05）.A组TT、E2较B、C组差异有统计学意义（P＜0.05）.TT与CTX-1、BGP显著相关（P＜0.05）.E2与CTX-1、BGP显著相关（P＜0.05）.结论 肥胖所致TT低下及E2升高与骨代谢存在密切关系,积极控制肥胖程度有助于降低骨质疏松发生率. |
| 关 键 词： | 骨质疏松 骨密度 性激素 骨代谢 |
Bone Betabolism and Sex Hormone Levels and Their Correlation in Obese Patients with Osteoporosis |
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| LV Tao,YU Zhi-jun,ZHANG Yuan. Bone Betabolism and Sex Hormone Levels and Their Correlation in Obese Patients with Osteoporosis[J]. Journal of Kunming Medical College, 2014, 35(6): 94-96,100 | |
| Authors: | LV Tao YU Zhi-jun ZHANG Yuan |
| Affiliation: | 1.Dept. of Laboratory Diagnosis,Affiliated Red Cross Hospital of Xi＇an Jiaotong University,Xi＇an Shanxi 710054; 2.Dept. of Laboratory Diagnosis,The Eighth Hospital of Xi＇an,Xi＇an Shanxi 710061; 3.Dept. of The Forth Hospital of Xi＇an,Xi＇an Shanxi 710004,China) |
| Abstract: | Objective To study bone metabolism and hormone levels and their correlation in obese patients with osteoporosis.Methods 76 patients with osteoporosis included 39 cases of obesity with osteoporosis （A group ）,37 cases of osteoporosis alone （B group）,and the other 40 cases of healthy men were selected as the control group （C group） 3 groups of patients were examined three indicators of bone metabolism,lipids and sex hormones.Results CTX-1,BGP of A group was significantly higher than B,C group （P＜0.05）,CTX-1,BGP of B group was significantly higher than the C group （P＜0.05）.TG,TC,HDL,LDL of A group had significant difference with B,C group （P＜0.05）,LDL of B group was significantly higher than the C group （P＜ 0.05）.TT,E2 of A group had a significant difference with B,C group （P ＜0.05）.TT and CTX-1,BGP was significantly correlated （P ＜0.05） E2 and CTX-1,BGP showed significant correlation （P ＜0.05） Conclusion Obesity caused elevated E2 and decreased TT has a close relationship with hone metabolism,actively controlling the degree of obesity can help reduce the incidence of osteoporosis. |
| Keywords: | Osteoporosis Bone Sex hormone Bone metabolism |
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