以冻结步态为首发症状的运动障碍性疾病临床分析和文献复习

目的：探讨以冻结步态为首发症状的一组运动障碍性疾病的临床特点。方法：对8例早期出现冻结步态的患者进行前瞻性研究。结果：8例患者经过1～3年的临床随访，2例临床诊断为进行性核上性眼肌麻痹（PSP），1例为路易体痴呆（DLB），1例为帕金森综合征（PS），1例为正常压力脑积水（NPH），3例为原发性进行性冻结步态（PPFG）。结论：冻结步态可以是多种运动障碍疾病的早期突出表现。

A Group of Movement Disorder with Primary Symptom of Freezing Gait

Aim:To explore the characteristics of a group of movement disorders which showed primary symptom of freezing gait.Methods: To study prospectively clinical materials of 8 patients who showed primary symptom of freezing gait.Results: Of eight patients followed up for 1 to 3.5 years,two were diagnosed as progressive supranuclear palsy(PSP),one diagnosed as dementia diffuse Lewy body(DLB),one was parkinsonism,one was normal pressure hydrocephalus(NHP),three were primary progressive freezing gait (PPFG).Conclusion: Freezing gait is a sign with diverse causes,which may be the early predominant symptom of some movement disorders.