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STUDIES ON NUTRITION AND PRECANCEROUS LESIONS OF THE ESOPHAGUS IN THE ADOLESCENTS
作者姓名:王立东  郭花芹  裘宋良  杨欢瑞  Jurgen Wahrendorf  Jenny Chang-claude
作者单位:Institute of Henan Medical Sciences,Henan medical University,Zhengzhou,Henan,Institute of Henan Medical Sciences,Henan medical University,Zhengzhou,Henan,Institute of Henan Medical Sciences,Henan medical University,Zhengzhou,Henan,Institute of Henan Medical Sciences,Henan medical University,Zhengzhou,Henan,German Cancer Research Center,Institute of Epidermiology,Biometry,Federal Republic of Germany,German Cancer Research Center,Institute of Epidermiology,Biometry,Federal Republic of Germany
摘    要:This paper reports the prevalence of chronic esophagitis and nutritional status among 538 young persons aged 15 to 26 years from the high risk area for esophageal cancer. Of these subjects, 166 were from households with history of esophageal cancer and 372 were from households without history of esophageal cancer. The Incidences of chronic esophagltis among male and female adolescents were 37. 6% and 36% respectively, which was significantly higher than those in the low risk area (17%). The frequency of chronic esophagltis in the adolescents in the households with history of esophageal cancer was aiso higher than in those In the households without history of esophageal cancer. The deficiencies of vitamins, especially of riboflavin and ascorbate, are prevalent and severe among these adolescents. Ascorbate deficiency Is correlated with the severity of the chronic esophagltis. These results indicate that chronic esophagltis may be involved in the natural history of esophageal carclnogenesis. Nutrient defic


Studies on nutrition and precancerous lesions of the esophagus in the adolescents
Lidong Wang,Huaqin Guo,Songliang Qiu,Guanrui Yang,Jurgen Wahrendorf,Jenny Chang-claude.STUDIES ON NUTRITION AND PRECANCEROUS LESIONS OF THE ESOPHAGUS IN THE ADOLESCENTS[J].Chinese Journal of Cancer Research,1992,4(4):69-75.
Authors:Lidong Wang  Huaqin Guo  Songliang Qiu  Guanrui Yang  Jurgen Wahrendorf  Jenny Chang-claude
Institution:1. Institute of Henan Medical Sciences, Henan medical University, Zhengzhou, Henan
2. German Cancer Research Center, Institute of Epidemiology and Biometry, Federal Republic of Germany
Abstract:This paper reports the prevalence of chronic esophagitis and nutritional status among 538 young persons aged 15 to 26 years from the high risk area for esophageal cancer. Of these subjects, 166 were from households with history of esophageal cancer and 372 were from households without history of esophageal cancer. The Incidences of chronic esophagltis among male and female adolescents were 37. 6% and 36% respectively, which was significantly higher than those in the low risk area (17%). The frequency of chronic esophagltis in the adolescents in the households with history of esophageal cancer was aiso higher than in those In the households without history of esophageal cancer. The deficiencies of vitamins, especially of riboflavin and ascorbate, are prevalent and severe among these adolescents. Ascorbate deficiency Is correlated with the severity of the chronic esophagltis. These results indicate that chronic esophagltis may be involved in the natural history of esophageal carclnogenesis. Nutrient deficiencies may create an environment favorable to the development of precancerous lesions.
Keywords:esophageal tumor  esophagltis  nutrition of children  precancerous status  
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