The effects of haloperidol on the EEG spectrum |
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| Authors: | G. H. Wieneke W. M. A. Verhoeven H. G. M. Westenberg H. de Wilde F. H. Lopes da Silva H. M. van Praag W. Storm van Leeuwen |
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| Affiliation: | (1) Department of Clinical Neurophysiology, State University Utrecht, Utrecht, The Netherlands;(2) Department of Psychiatry, State University Utrecht, Utrecht, The Netherlands;(3) Bran Research Department, Institute of Medical Physics TNO, Utrecht, The Netherlands |
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| Abstract: | ![]()
A placebo-controlled study with six normal volunteers was carried out using 1 mg haloperidol IM. In some EEG frequency bands, the power density due to haloperidol appeared to increase or decrease depending on the subject. Nevertheless, if the results of the six subjects are taken together, the effects of haloperidol are in agreement with the literature. No correlation was found between plasma concentration of haloperidol and EEG response. Some methodological problems are discussed. |
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| Keywords: | Haloperidol EEG spectrum Drug classification |
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