合心爽,硝酸甘油治疗不稳定型心绞痛对比研究

目的 比较用硝酸甘油和合心爽治疗９８例不稳定型心绞痛的疗效。方法 随机分组，分别静滴合心爽和硝酸甘油，以难治性心绞痛、心肌梗塞或缺血性猝死为治疗终点。结果 发展为难治性心绞痛或心肌梗塞病例在合心爽组为５人，硝酸甘油组为１１人，发生心肌梗塞者合心爽组３人，硝酸甘油８人，缺血性猝死者合合爽组无，硝酸甘油组１人。结论 静脉用合心爽治疗不稳定型心绞痛疗效优于硝酸甘油（Ｐ〈０．００１）。

A Comparative Study of the Curative Effect of Diltiazemi Hydrochloridi and Nitroglycerin for Unstable Angina pectoris

Objective:Among 98 cases of angina pectoris of unstable type a comparison was made between the curative effect of Diltiazemi Hydrochloridi and that of Nitroglycerin.Method:Divide the patients at a random into two groups and administered Diltiazemi and Nitroglycerin respectively by intravenous drip.The treatment ended in refractory angina pectoris,cardiac infarction or ischemic sudden death.Result: 5 patients in the Diltiazemi group and 11 patients in the Nitroglycerin group developed refractory angina pectoris.3 patients in the Diltiazemi group and 8 patients in the Nitroglycerin group had cardiac infarction.One patient in the Nitroglycerin group and none in the Diltiazemi group ended in ischemic sudden death.Conclusion:intravenous Diltiazemi is superior to Nitroglycerin for the treatment of unstable angina pectoris(p<0.001).