复方丹参注射液联合脑蛋白水解物治疗新生儿缺氧缺血性脑病

目的 探讨复方丹参与脑蛋白水解物联合应用治疗新生儿缺氧缺血性脑病(HIE)的疗效.方法 将90例新生儿缺氧缺血性脑病患儿随机分为两组,对照组45例采用常规三项支持疗法和对症治疗,治疗组45例在对照组的治疗基础上加用复方丹参注射液与脑蛋白水解物注射液联合应用.结果 治疗组总有效率为95.56%;对照组为77.78%,两组比较有显著性差异(P＜0.05).结论 复方丹参注射液与脑蛋白水解物注射液联合应用治疗HIE疗效显著.

Clinical Observation on Compound Danshen and Cerebrolysin Vial Combination Therapy in Treating Cases of Neonatal Hypoxic Ischemie Encephalopathy

Objective To evaluate the clinical efficacy of compound Danshen and Cerebrolysin Vial combination therapy in treating cases of neonatal hypoxic ischemic encephalopathy(HIE).Methods 90 cases of neonatal HIE hospitalized form May 2005 to September 2006 were randomly separated into an experiment group and a control group.On the basis of conventional trigeminal supporting treatment,the experiment group was treated with additional compound Danshen and Cerebrolysin Vial combination therapy.At the end of therapeutic courses,overall effective rate was evaluated.Results The overall effective rate of the experiment group was 95.56%,comparing with a 77.78% overall effective rate in the control group.The overall effective rate of the experiment group was significantly different from the control group (P＜0.05).Conclusions Compound Danshen and Cerebrolysin Vial combination therapy was significantly effective in treating neonatal hypoxic ischemic encephalopathy.This therapy is recommendable in daily clinical treatment of HIE.