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去甲长春花碱联合顺铂治疗晚期非小细胞肺癌疗效观察
引用本文:朴相茂,崔南奎,朴美慈.去甲长春花碱联合顺铂治疗晚期非小细胞肺癌疗效观察[J].吉林医学,2003,24(3):221-222.
作者姓名:朴相茂  崔南奎  朴美慈
作者单位:延边肿瘤医院化疗科 吉林延吉133000 (朴相茂,崔南奎),延边肿瘤医院化疗科 吉林延吉133000(朴美慈)
摘    要:目的:观察去甲长春花碱(NVB)、顺铂(DDP)联合治疗非小细胞肺癌疗效。方法:自2000年11月至2002年4月,对21例晚期非小细胞肺癌采用去甲长春花碱联合顺铂的化疗方案治疗。结果:全组21例,部分缓解8例,总有效率为38%。主要毒性反应为骨髓抑制,其中白细胞下降Ⅲ、Ⅳ度者达57.1%。结论:去甲长春花碱联合顺铂治疗非小细胞肺癌疗效较好。

关 键 词:去甲长春花碱  顺铂  非小细胞肺癌
文章编号:1004-0412(2003)03-0221-02
修稿时间:2002年11月15

Therapeutic effect of navelbine plus cisplatin in treatment of non-small cell lung cancer
PIAO Xiang-mao,CUI Nan-kui,PIAO Mei-ci.Therapeutic effect of navelbine plus cisplatin in treatment of non-small cell lung cancer[J].Jilin Medical Journal,2003,24(3):221-222.
Authors:PIAO Xiang-mao  CUI Nan-kui  PIAO Mei-ci
Abstract:Objective To evaluate the efficacy of navelbine plus cisplatin in treatment of non-small cell lung cancer(NSCLC).Method From January2000to April2002,twenty-one patients with advanced NSCLC were enrolled in this study.They were treated with chemotherapy scheme of navelbine plus cispatin.Results Eight patients had partial response.An overall response rate was38%.The toxicity was chiefly hematology in the form of neutropenia,57.1%in gradeⅢandⅣ.Conclusion A high response rate was obtained in advanced NSCLC treated by chemotherapy of navelbine plus cispatin.
Keywords:Navelbine  Cisplatin  NSCLC
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