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血管内皮生长因子与肾细胞癌
引用本文:周术奎,王顺平,王跃闽. 血管内皮生长因子与肾细胞癌[J]. 国际肿瘤学杂志, 2012, 39(2): 148-151
作者姓名:周术奎  王顺平  王跃闽
作者单位:同济大学附属东方医院泌尿外科, 上海,200120
摘    要:
血管内皮生长因子(VEGF)在肾细胞癌组织中高表达,主要受VHL基因和组织缺氧调控,可作为判断肾细胞癌患者肿瘤进展和预后的标志物.近年来将抗VEGF靶向药物用于肾细胞癌治疗,取得良好的临床疗效.

关 键 词:血管内皮生长因子类  肾肿瘤  治疗应用

Vascular endothelial growth factor and renal cell carcinoma
ZHOU Shu-kui , WANG Shun-ping , WANG Yue-min. Vascular endothelial growth factor and renal cell carcinoma[J]. Journal of International Oncology, 2012, 39(2): 148-151
Authors:ZHOU Shu-kui    WANG Shun-ping    WANG Yue-min
Abstract:
Vascular endothelial growth factor(VEGF)is high expression in the organization of renal cell carcinoma and mainly regulate by VHL gene and hypoxic of organization. Moreover, it can be a biomarker to judge renal cell carcinoma tumor progression and prognostic. In recent years, anti-VEGF targeted drugs are used for the treatment of renal cell carcinoma and receive meaningful clinical benefits.
Keywords:Vascular endothelial growth factors  Kidney neoplasms  Therapeutic uses
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