利用光强分布测量生物组织的光学特性

目的 设计一种利用光强分布测量生物组织光学性质的新方法.方法 利用光纤测定了650 nm连续激光入射到半无限大生物组织模拟液Intralipid- 10％中的光强分布,由漫射强度表达式,通过非线性拟合的方法确定了生物组织的光学特性参数.利用确定的光学参数和光强公式可以了解样品中光强的分布和各点光强的各向异性.结果 通过与现有的结果比较,证明这种方法是可行的.结论 此研究能对液体样品内部的散射性质有更全面的了解,为液体如生物医学用的液体样品的测量和激光诊疗提供有用的信息.

Determination of optical properties by measuring intensity distribution in tissue sample

Objective To design a new method of determining optical properties of biological tissue by measuring light intensity distribution. Methods The light distribution in Intralipid-10% suspension at 650 nm was measured by optical fiber probe. The optical parameters were derived from nonlinear regression of the diffusion equation for intensity. The distribution and anisotropy of intensity was abtained by the determined optical parameters and the diffusion equation for intensity. Results This new method was feasible by comparing the experimental data with published results. Conclusion The experiment results would provide useful information for radiative transfer equation, marine optical remote sensing measurement and laser therapeutic applications.