加味四君子汤对烧伤患者血清清蛋白和前清蛋白的影响

目的 观察加味四君子汤对烧伤患者血清清蛋白(ALB)和前清蛋白(PA)含量的影响.方法 采用随机对照法将50例30%~50%全身性烧伤面积(TBSA)患者分为治疗组与对照组,分别服用加味四君子汤和等量生理盐水10 d,观察患者消化功能,检测治疗前、治疗开始后1~10 d血清ALB和PA含量.结果 治疗组和对照组消化功能恢复的临床表现分别为16例(64%)和10例(40%)显效,两组比较差异有统计学意义(P<0.05).对照组治疗期间血清PA和ALB含量持续下降,至治疗开始后10 d PA为(97.11±2.84)mg/L、ALB为(28.04±1.62)mg/L,分别较开始前下降52.9

Effects of modified Sijunzi Decoction on serum albumin and prealbumin in burn patient

Objective To observe the effect of modified Sijunzi Decoction on the serum content of albumin(ALB) and prealbumin(PA) in burn patient.Methods Fifty burn patients with 30%-50% total body surface area(TBSA) were randomly divided into the treatmant group and the control group.Based on the conventional therapy for two groups,Sijunzi Decoction 100mL or normal saline 100mL were taken orally twice a day respectively.The therapeutic course was 10 d.Before and after treatment,the improvement of digestive function was observed,at the same time the serum contents of ALB and PA were measured.Results After therapy,there were 16 cases(64%) in the treatment group and 10 cases(40%) in the control group showing the distinct improvement of digestive function(P<0.05).The contents of ALB and PA in serum were decreased significantly in the control group during treatment,the rate of decline was 52.95% and 20.23% respectively.But the contents of ALB and PA in serum were increased in the treatment group from 4-7 d after taking Sijunzi Decoction,at the end of therapeutic course PA reaching(253.41±6.07)mg/L,ALB reaching(43.31±2.46)mg/L,there had significant difference in the serum contents of ALB and PA between the control group and treatment group(P<0.01).Conclusion Modified Sijunzi Decoction in treating burn could effectively raise the contents of ALB and PA in serum and improve the digestive function of burn patients,which is worth being popularized in clinic.