| PINP在诊断骨质疏松症中的应用 |
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| 引用本文： | 邢学农,任安,杨静,陈若平,叶山东,罗伟英,汤涛,程永福. PINP在诊断骨质疏松症中的应用[J]. 中国临床保健杂志, 1999, 0(3) |
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| 作者姓名： | 邢学农 任安 杨静 陈若平 叶山东 罗伟英 汤涛 程永福 |
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| 作者单位： | 安徽省立医院内分泌科，安徽省立医院内分泌科，安徽省立医院内分泌科，安徽省立医院内分泌科，安徽省立医院内分泌科，安徽省立医院内分泌科，安徽省立医院内分泌科 230001，230001，230001，安徽省立医院内分泌科，230001，230001，230001，230001，230001 |
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| 摘 要： | 目的 探讨用于诊断骨质疏松症的较敏感生化指标。方法 采用放免法测定46例骨质疏松性骨痛。34例非重力骨折及24例健康者血PINP水平和其它相关指标。结果 骨痛和骨折两组患者PINP水平均明显高于正常对照组(P<0.01);PINP与其它骨形成指标有较好相关性。结论 PINP由于在血循环中较稳定,可作为诊断骨质疏松症的较敏感指标。
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| 关 键 词： | PINP 骨质疏松性骨痛 非重力骨折 生化指标 |
Applycation of PINP in the Diagnosis of Osteoporosis |
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| Xing Xuenong,Ren An,Yang Jing,et al,Depart-ment of Endocrinology,Anhui Prouincial Hospital,Hefei. Applycation of PINP in the Diagnosis of Osteoporosis[J]. Chinese Journal of Clinical Healthcare, 1999, 0(3) |
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| Authors: | Xing Xuenong Ren An Yang Jing et al Depart-ment of Endocrinology Anhui Prouincial Hospital Hefei |
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| Affiliation: | Xing Xuenong,Ren An,Yang Jing,et al,Depart-ment of Endocrinology,Anhui Prouincial Hospital,Hefei 230001 |
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| Abstract: | Objective Exploring sensitive biochemical criterion for diagnosis of osteoporosis. Methods 80 Patients were divided into two groups:46 with osteoporotic osteodynia (Group I ),34 with fragility fractures (Group II ).And the control was. 24 healthy persons (Group Ⅲ ).Forearm BMD as well as serum PINP were measured in all the subjects.And other plasma criteria: BGP PTH CT AKP Ca P were studied too. Results We found a significant increase in the level of PINP in both groups I and II ,compared with group Ⅲ (P< 0.01).The value of PINP had a positive correlation with that of other bone formation criteria (BGP and AKP) and a negative correlation with BMD. Conclusion Since the serum level of PINP had a good correlation with BGP AKP,and had a higher stability in plasma.it is considered as a sensitive criterion, in the diagnosis of osteoporosis. |
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| Keywords: | PINP Osteoporolic osteodynia Fragility fracture Biochemical criterion |
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