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Effects of Fujian tablet on Nogo-A mRNA expression and plasticity of the corticospinal tract in a rat model of focal cerebral ischemia
Authors:Wei Liu  Yonghong Zhou  Qing Jia  Bingbing Han  Guoli Zhang
Affiliation:Wei Liu1,Yonghong Zhou2,Qing Jia3,Bingbing Han4,Guoli Zhang5 1Department of Encephalopathy,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong Province,China 2Department of Traditional Chinese Medicine,Medical College of Qingdao University,Qingdao 266071,China 3Institute of Basic Medicine,Shandong Academy of Medical Science,Jinan 250062,China 4College of Basic Medical Sciences,Jinan 250355,C...
Abstract:
The present study investigated the effects of Fujian tablet, a Chinese medicine compound that can nourish liver and kidney, on corticospinal tract plasticity and cervical cord microenvironment in rats with focal cerebral ischemia. Results showed that motor function of rats with right proximal middle cerebral artery occlusion was significantly improved following treatment with Fujian tablet, 9 g crude drug/kg. Anterograde tracing revealed significantly increased biotinylated dextran amine expression in the d...
Keywords:Fujian tablet  focal cerebral ischemia  corticospinal tract  Nogo-A mRNA  Chinese herbal formula  neural plasticity  neural regeneration  
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