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-94 G/A polymorphism in the dopamine D1 receptor gene is associated with schizophrenia in a Chinese Han population from Shandong province |
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| Authors: | Zhaoyun Du Guangxin Wang Yuebing Zhang Yiren Cheng Chuan’an Zhu |
| Affiliation: | 1Department of Laboratory Medicine, Jining Medical College, Jining 272067, Shandong Province, China 2Institute of Pediatrics, Qilu Children’s Hospital, Shandong University, Jinan 250022, Shandong Province, China 3Department of Psychiatry, Second Affiliated Hospital of Jining Medical College, Jining 272051, Shandong Province, China 4Department of Laboratory, First People’s Hospital of Jining, Jining 272001, Shandong Province, China |
| Abstract: | The correlation between -94 G/A polymorphism in the dopamine D1 receptor gene and schizophrenia remains poorly understood despite extensive research. This study sought to evaluate the genotypes and allele frequencies of the -94 G/A polymorphism in the dopamine D1 receptor gene by real-time PCR using TaqMan fluorescent probes. One hundred and sixty-two patients with schizophrenia and 101 healthy controls living in Shandong province of China were evaluated. Experimental results showed that the G/A genotype di... |
| Keywords: | dopamine D1 receptor gene single nucleotide polymorphism schizophrenia |
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