| 羟基喜树碱联合化疗治疗晚期非小细胞肺癌的临床观察 |
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| 引用本文： | 孙文辉,吴昌平,朱丽娜.羟基喜树碱联合化疗治疗晚期非小细胞肺癌的临床观察[J].中国肿瘤临床与康复,2003,10(3):229-230. |
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| 作者姓名： | 孙文辉 吴昌平 朱丽娜 |
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| 作者单位： | 苏州大学附属第三医院肿瘤科,常州,213003 |
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| 摘 要： | 目的观察羟基喜树碱联合化疗治疗晚期非小细胞肺癌的疗效和毒副作用.方法 56例晚期非小细胞肺癌患者中,50例肺腺癌接受HEMe方案化疗,6例肺鳞癌接受HE方案化疗.结果总有效率为39.3%,肺腺癌有效率为42.0%,肺鳞癌有效率为16.7%.结论羟基喜树碱联合化疗治疗非小细胞肺癌疗效好,毒副作用小,费用低,值得临床推广应用.
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| 关 键 词： | 肺肿瘤/化学疗法 羟基喜树碱 |
| 文章编号： | 1005-8664(2003)03-0229-02 |
| 修稿时间： | 2002年5月30日 |
Clinical observation of the hydroxycamptothecin based on combination chemotherapy in advanced non-small cell lung cancer |
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| SUN Wen-hui,WU Chang-ping,ZHU Li-na.Clinical observation of the hydroxycamptothecin based on combination chemotherapy in advanced non-small cell lung cancer[J].Chinese Journal of Clinical Oncology and Rehabilitation,2003,10(3):229-230. |
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| Authors: | SUN Wen-hui WU Chang-ping ZHU Li-na |
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| Abstract: | Objective To evaluate the efficacy and safety profile of 10-hydroxycamptothecin based on combination chemotherapy in advanced non-small cell lung cancer (NSCLC) .Methods Of 56 NSCLC patients, 50 cases of lung adenocarcinoma were treated with HEMe and 6 cases of squamous cell carcinoma with HE regimens. Results In adenocarcinoma patients 21 cases achieved partial response(42.0%),and in squamous cell carcinoma patients 1 achieved partial response (16.7%). The overall response rate was 39.3 % . Conclusion 10-hydroxycamptothecin based on combination chemotherapy is active and tolerable in advanced NSCLC. |
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| Keywords: | Lung neoplasm/chemotherapy Hydroxycamptothecin |
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