| 瑞舒伐他汀对2型糖尿病患者低密度脂蛋白胆固醇和超敏C反应蛋白的影响 |
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| 引用本文： | 王艳梅. 瑞舒伐他汀对2型糖尿病患者低密度脂蛋白胆固醇和超敏C反应蛋白的影响[J]. 中国药业, 2011, 20(22): 37-39 |
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| 作者姓名： | 王艳梅 |
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| 作者单位： | 江苏省徐州市第六人民医院内分泌科,江苏,徐州,221000 |
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| 摘 要： | 目的探讨瑞舒伐他汀对2型糖尿病患者低密度脂蛋白胆固醇(LDL-C)和高敏C反应蛋白(hsCRP)的影响。方法将2型糖尿病患者随机分为A组、B组、C组,分别予以安慰剂、辛伐他汀(20 mg/d)和瑞舒伐他汀(10 mg/d)连续治疗3个月,于治疗前后分别测定患者低密度脂蛋白和超敏C反应蛋白水平。结果 B组、C组治疗后低密度脂蛋白和超敏C反应蛋白水平均低于同组治疗前水平(P<0.05);C组治疗后低密度脂蛋白和超敏C反应蛋白水平均低于A组、B组治疗后水平(P<0.05)。结论瑞舒伐他汀能降低2型糖尿病患者的低密度脂蛋白和超敏C反应蛋白水平且效果优于辛伐他汀,在预防2型糖尿病患者的心血管事件方面可能起到重要作用。
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| 关 键 词： | 瑞舒伐他汀 2型糖尿病 低密度脂蛋白胆固醇 超敏C反应蛋白 |
Effects of Rosuvastatin on LDL-C and hs-CRP in Patients with Type 2 Diabetes Mellitus |
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| Wang Yanmei. Effects of Rosuvastatin on LDL-C and hs-CRP in Patients with Type 2 Diabetes Mellitus[J]. China Pharmaceuticals, 2011, 20(22): 37-39 |
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| Authors: | Wang Yanmei |
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| Affiliation: | Wang Yanmei(Department of Endocrinology,Xuzhou Sixth People's Hospital,Xuzhou,Jiangsu,China 221000) |
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| Abstract: | Objective To investigate the effects of rosuvastatin on low density lipoprotein cholesterol(LDL-C) and high sensitivity C-reactive protein(hs-CRP) in the patients with type 2 diabetes mellitus(T2DM).Methods The patients with T2DM were divided into group A,B and C and given placebo,simvastatin 20 mg and rosuvastatin 10 mg once a day respectively for 3 months.LDL-C and hs-CRP were measured before and after treatment.Results LDL-C and hs-CRP after treatment in the group B and C was lower than those before trea... |
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| Keywords: | rosuvastatin T2DM LDL-C hs-CRP |
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