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| Livin、Ki-67蛋白在胃癌中的表达及意义 | |
| 引用本文： | 李梅,姚乐,惠起源. Livin、Ki-67蛋白在胃癌中的表达及意义[J]. 现代肿瘤医学, 2011, 19(2): 302-304. DOI: 10.3969/j.issn.1672-4992.2011.02.33 |
| 作者姓名： | 李梅 姚乐 惠起源 |
| 作者单位： | 1. 陕西省肿瘤医院,陕西,西安,710061 2. 榆林市第一医院,陕西,榆林,719000 3. 延安大学附属医院,陕西,延安,716000 |
| 摘 要： | 目的:通过检测胃癌组织中Livin、Ki-67表达与其临床病理指标的关系,探讨两者表达的相关性及在癌变发生发展中的意义。方法:采用免疫组织化学方法测定Livin、Ki-67在40例胃癌中的表达,分析与胃癌临床病理指标的关系。结果:Livin和Ki-67与淋巴结转移、分化程度有统计学关联(P<0.05);与性别、年龄、不同浸润深度、不同临床分期间无关(P>0.05)。Livin、Ki-67在胃癌组织中的表达无关联(P>0.05)。结论:Livin、Ki-67可能有助于判断胃癌的恶性程度及进展情况,对于胃癌手术的根治和术后化疗有一定指导意义。 |
| 关 键 词： | 胃癌 Livin Ki-67 免疫组化 |
Expression of Livin and Ki-67 in gastric cancer and significance |
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| LI mei,YAO Le,HUI Qi-yuan. Expression of Livin and Ki-67 in gastric cancer and significance[J]. Journal of Modern Oncology, 2011, 19(2): 302-304. DOI: 10.3969/j.issn.1672-4992.2011.02.33 | |
| Authors: | LI mei YAO Le HUI Qi-yuan |
| Affiliation: | LI mei1,YAO Le2,HUI Qi-yuan31Department of Radiotherapy,Shaanxi Tumor Hospital,Xi,an 710061,China,2Department of Radiation Oncology,the First People of Yulin,Yulin 719000,3Medical College of Yan,an University,Yan,an 716000 |
| Abstract: | Objective:To study the Livin,Ki-67 expression in gastric cancer in and its clinical significance.Methods:To determine Livin,Ki-67 in 40 cases of gastric cancer by immunohistochemistry.Results:Livin and Ki-67 were related to lymph node metastasis,(P<0.05);on relation with gender,age,depth of invasion,clinical stages(P> 0.05).Livin,Ki-67 expression in gastric cancer was not related(P> 0.05).Conclusion:Livin,Ki-67 may help determine the degree of malignancy of gastric cancer and the progress of gastric cancer. |
| Keywords: | gastric carcinom livin ki-67 immunohistochemistry |
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