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桦褐孔菌乙醇提取物对急性肝损伤小鼠肝脏的保护作用
引用本文:吴艳玲,南极星,朴惠善. 桦褐孔菌乙醇提取物对急性肝损伤小鼠肝脏的保护作用[J]. 延边医学院学报, 2008, 31(1): 25-27
作者姓名:吴艳玲  南极星  朴惠善
作者单位:延边大学药学院 吉林延吉133000
摘    要:[目的]探讨桦褐孔菌乙醇提取物对肝脏的保护作用.[方法]腹腔注射四氯化碳豆油溶液制作急性肝损伤小鼠模型,以肝脏及脾脏质量比、血清中天门冬氨酸氨基转移酶(AST)及丙氨酸氨基转移酶(ALT)为指标,观察桦褐孔菌乙醇提取物对小鼠肝脏的保护作用.[结果]桦褐孔菌乙醇提取物组小鼠血清中ALT,AST值明显低于模型组.[结论]桦褐孔菌乙醇提取物对小鼠肝脏具有保护作用.

关 键 词:肝疾病  植物,药用  小鼠
文章编号:1000-1824(2008)01-0025-02
修稿时间:2007-12-20

Protective effects of alcohol extracts of the Inonotus obliquus on acute liver failure in mice
WU Yan-ling,NAN Ji-xing,PIAO Hui-shan. Protective effects of alcohol extracts of the Inonotus obliquus on acute liver failure in mice[J]. Journal of Medical Science Yanbian University, 2008, 31(1): 25-27
Authors:WU Yan-ling  NAN Ji-xing  PIAO Hui-shan
Abstract:OBJECTIVE To study the effects of alcohol extracts of the Inonotus obliquus on hepatic iniury.METHODSThe acute hepatic injury induced by CCl4,and the coefficient of liver and spleen,aspartate amino transferase(ALT) and alanine aminotransferase(AST) in serum of mice were determined to study the effects of extractions of the Inonotus obliquus.RESULTSserum ALT and AST in alcohol extractions group was lower than that of other groups.CONCLUSIONThe extracts of Inonotus obliquus could obviously increase protective effect against liver injury.
Keywords:liver diseases  plants  medicinal  mice
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