利多卡因注射液滴眼用于激光角膜原位磨镶术表面麻醉的效果研究

目的探讨2％利多卡因注射液滴眼用于准分子激光角膜原位磨镶术（LASIK）表面麻醉的效果。方法100例（200眼）随机分成利多卡因组和奥布卡因组，每组50例（100眼）。两组分别在两种药物的表面麻醉下进行LASIK，根据术中患者对疼痛和触觉的感受评价麻醉效果。结果利多卡因组中98眼能顺利完成手术，2眼稍感疼痛，追加滴利多卡因1滴后顺利完成手术。奥布卡因组99眼顺利完成手术，1眼稍感不适，未做处理，也顺利完成手术。结论2％利多卡因注射液滴眼用于LASIK表面麻醉效果良好。

The effect of Lidocaine on topical anesthesia for LASIK

Objective To discuss the effect of 2% Lidocaine solution for injection on topical anesthesia for laser in situ keratomileusis (LASIK). Methods Totally 100 cases (200 eyes) were randomly divided into two groups,2% Lidocaine group and Oxybuprocaine group. Each group contained 50 cases ( 100eyes). LASIK was done under the topical anesthesia of those two medicine respectively. The anesthetic effect was assessed by the feeling of pain and tactile perception of the patients. Results The surgery was done smoothly in 98 eyes under Lidocaine anesthesia. There was mild pain in two eyes during the surgery. The pain disappeared when an additional drop of Lidocaine was used. In Oxybuprocaine group, the surgery was done smoothly in 99 eyes. There was mild discomfort in one eye, and the surgery was done without additional treatment. Conclusion 2% Lidocaine injection can provide good topical anesthetic effect for LASIK.